Acetone → Phthalidyl o-acetylsalicylate

HRID 2328786Notes

Reaction equation

HRID 2328786 reaction equation
[Br:21][CH:22]1[O:23][C:24](=[O:25])[c:26]2[cH:27][cH:28][cH:29][cH:30][c:31]21.[C:1]([CH3:2])(=[O:3])[C:4]1([OH:13])[CH:5]([C:6](=[O:7])[OH:8])[CH:9]=[CH:10][CH:11]=[CH:12]1.[CH3:14][CH2:15][N:16]([CH2:17][CH3:18])[CH2:19][CH3:20].[CH3:32][C:33](=[O:34])[CH3:35]>>[C:1]([CH3:2])(=[O:3])[C:4]1([OH:13])[CH:5]([C:6](=[O:7])[O:8][CH:22]2[O:23][C:24](=[O:25])[c:26]3[cH:27][cH:28][cH:29][cH:30][c:31]32)[CH:9]=[CH:10][CH:11]=[CH:12]1

Participants

5

Reactant 4

HCID 180AcetoneHCID 8471TriethylamineHCID 962181(3H)-Isobenzofuranone, 3-bromo-HCID 178417052-Acetylsalicylic acid

Product 1

HCID 70571343Phthalidyl o-acetylsalicylate

Sources & evidence

ORD record
ord-436c5bf1e03748a3aba1f6f76f4c71ae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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