p-Toluidine → (2-Amino-5-methyl-phenyl)-(2,6-difluoro-phenyl)-methanone

HRID 2328934Notes

Reaction equation

HRID 2328934 reaction equation
[CH3:18][c:19]1[cH:20][cH:21][c:22]([NH2:23])[cH:24][cH:25]1.[F:26][c:27]1[c:28]([C:29](=[O:30])[Cl:31])[c:32]([F:36])[cH:33][cH:34][cH:35]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([Cl:6])[cH:7][c:8]1[C:9]([c:10]1[cH:11][cH:12][c:13]([F:14])[cH:15][cH:16]1)=[O:17]>>[CH3:18][c:19]1[cH:20][c:21]([C:29]([c:28]2[c:27]([F:26])[cH:35][cH:34][cH:33][c:32]2[F:36])=[O:30])[c:22]([NH2:23])[cH:24][cH:25]1

Participants

4

Reactant 3

HCID 7813p-ToluidineHCID 874382,6-Difluorobenzoyl chlorideHCID 109559554-Chloro-2-(4-fluorobenzoyl)aniline

Product 1

HCID 67505674(2-Amino-5-methyl-phenyl)-(2,6-difluoro-phenyl)-methanone

Sources & evidence

ORD record
ord-2f6ca251495b47b3be675f8e559a28ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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