Trifluoroacetic acid → N-{1-[4-(3-Dimethylamino-phenyl)-4-hydroxy-cyclohexyl]-azetidin-3-yl}-2-(1-methyl-5-trifluoromethyl-1H-indazol-3-ylamino)-acetamide
Reaction equation
[CH3:31][N:32]([c:33]1[cH:34][c:35]([C:39]2([OH:46])[CH2:40][CH2:41][C:42](=[O:45])[CH2:43][CH2:44]2)[cH:36][cH:37][cH:38]1)[CH3:47].[F:24][C:25]([F:26])([F:27])[C:28]([OH:29])=[O:30].[NH:1]1[CH2:2][CH:3]([NH:5][C:6]([CH2:7][NH:8][c:9]2[n:10][n:11]([CH3:22])[c:12]3[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][c:17]23)=[O:23])[CH2:4]1>>[N:1]1([CH:42]2[CH2:41][CH2:40][C:39]([c:35]3[cH:34][c:33]([N:32]([CH3:31])[CH3:47])[cH:38][cH:37][cH:36]3)([OH:46])[CH2:44][CH2:43]2)[CH2:2][CH:3]([NH:5][C:6]([CH2:7][NH:8][c:9]2[n:10][n:11]([CH3:22])[c:12]3[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][c:17]23)=[O:23])[CH2:4]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-864670b443054eaa89a7ef51a8e5b040
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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