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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2329184Generated: November 2, 2026

Tetrahydrofuran → 5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-3-prop-2-enyl-1-(1,1,1-trifluoro-2-hydroxy-2-methylpentan-3-yl)piperidin-2-one

https://huagongshe.com/reaction/2329184

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant(Trifluoromethyl)trimethylsilaneHCID 552549—
ReactantHCID 178438866HCID 178438866—
Product5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-3-prop-2-enyl-1-(1,1,1-trifluoro-2-hydroxy-2-methylpentan-3-yl)piperidin-2-oneHCID 178438868—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-4ef52341f5884b0fbbd8d1eed0edbe0c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)