Water → N-{2,4-difluoro-3-[hydroxy-(1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-phenyl}-3-methoxy-benzenesulfonamide
Reaction equation
[CH2:43]([N+:44]([CH2:45][CH2:46][CH2:47][CH3:48])([CH2:49][CH2:50][CH2:51][CH3:52])[CH2:53][CH2:54][CH2:55][CH3:56])[CH2:57][CH2:58][CH3:59].[F-:42].[F:1][c:2]1[c:3]([NH:30][S:31](=[O:32])(=[O:33])[c:34]2[cH:35][c:36]([O:40][CH3:41])[cH:37][cH:38][cH:39]2)[cH:4][cH:5][c:6]([F:29])[c:7]1[CH:8]([c:9]1[cH:10][n:11]([Si:18]([CH:19]([CH3:20])[CH3:21])([CH:22]([CH3:23])[CH3:24])[CH:25]([CH3:26])[CH3:27])[c:12]2[n:13][cH:14][cH:15][cH:16][c:17]12)[OH:28].[O:61]1[CH2:62][CH2:63][CH2:64][CH2:65]1.[OH2:60]>>[F:1][c:2]1[c:3]([NH:30][S:31](=[O:32])(=[O:33])[c:34]2[cH:35][c:36]([O:40][CH3:41])[cH:37][cH:38][cH:39]2)[cH:4][cH:5][c:6]([F:29])[c:7]1[CH:8]([c:9]1[cH:10][nH:11][c:12]2[n:13][cH:14][cH:15][cH:16][c:17]12)[OH:28]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5a0734f835984fb88cd677f23209231c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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