Dichloromethane → rac-(3R,4S)-1-Benzyl-3-(4-fluoro-phenyl)-4-nitro-pyrrolidine
Reaction equation
[CH3:1][O:2][CH2:3][N:4]([CH2:5][Si:6]([CH3:7])([CH3:8])[CH3:9])[CH2:10][c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1.[Cl:36][CH2:37][Cl:38].[F:17][c:18]1[cH:19][cH:20][c:21]([CH:24]=[CH:25][N+:26](=[O:27])[O-:28])[cH:22][cH:23]1.[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[CH2:3]1[N:4]([CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:5][CH:25]([N+:26](=[O:27])[O-:28])[CH:24]1[c:21]1[cH:20][cH:19][c:18]([F:17])[cH:23][cH:22]1Participants
5
Sources & evidence
- ORD record
- ord-fc5ed4c4aa1f4f3a9a90ffaa428e5b15
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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