Trifluoroacetic acid → HCID 15870914, compound

HRID 232943Notes

Reaction equation

HRID 232943 reaction equation
[CH:1]1([C:4]2[N:8]([CH2:9][C:10]3[CH:15]=[CH:14][C:13]([C:16]4[C:17]([C:22]([O:24]C(C)(C)C)=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=4)=[CH:12][CH:11]=3)[C:7]3[CH:29]=[C:30]([C:34]4[N:38]([CH3:39])[C:37]5[CH:40]=[CH:41][CH:42]=[CH:43][C:36]=5[N:35]=4)[CH:31]=[C:32]([CH3:33])[C:6]=3[N:5]=2)[CH2:3][CH2:2]1.FC(F)(F)C(O)=O>C(Cl)Cl>[CH:1]1([C:4]2[N:8]([CH2:9][C:10]3[CH:11]=[CH:12][C:13]([C:16]4[C:17]([C:22]([OH:24])=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=4)=[CH:14][CH:15]=3)[C:7]3[CH:29]=[C:30]([C:34]4[N:38]([CH3:39])[C:37]5[CH:40]=[CH:41][CH:42]=[CH:43][C:36]=5[N:35]=4)[CH:31]=[C:32]([CH3:33])[C:6]=3[N:5]=2)[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 15870918HCID 15870918, compound

Product 1

HCID 15870914HCID 15870914, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared analogously to Example 1 from tert.butyl 4'-[(2-cyclopropyl-4-methyl -6-(1-methylbenzimidazol-2-yl)-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylate and trifluoroacetic acid in methylene chloride.

Sources & evidence

ORD record
ord-a8500992dd594623a8a20ae8b2ba587e
Source dataset
uspto-grants-1997_01
Patent number
US05591762

Reaction notes

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