Tetrahydrofuran → (4-bromo-1-trityl-1H-imidazol-2-yl)(3-ethylphenyl)methanol

HRID 2329442Notes

Reaction equation

HRID 2329442 reaction equation
[Br:15][c:16]1[n:17][c:18]([CH:40]=[O:41])[n:19]([C:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[cH:20]1.[Br:1][c:2]1[cH:3][c:4]([CH2:8][CH3:9])[cH:5][cH:6][cH:7]1.[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:10][CH2:11][CH2:12][CH2:13][Li:14]>>[c:2]1([CH:40]([c:18]2[n:17][c:16]([Br:15])[cH:20][n:19]2[C:21]([c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)([c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[OH:41])[cH:3][c:4]([CH2:8][CH3:9])[cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 123170Benzene, 1-bromo-3-ethyl-HCID 862472204-bromo-1-trityl-1H-imidazole-2-carbaldehydeHCID 178418339Butyllithium

Product 1

HCID 68813719(4-bromo-1-trityl-1H-imidazol-2-yl)(3-ethylphenyl)methanol

Sources & evidence

ORD record
ord-c8456846baf848159f1921c6e2f544d1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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