Hydrochloric Acid → 4-[2-(Trifluoromethyl)phenyl]piperidin-4-ol

HRID 2329461Notes

Reaction equation

HRID 2329461 reaction equation
[ClH:25].[OH:1][C:2]1([c:15]2[c:16]([C:21]([F:22])([F:23])[F:24])[cH:17][cH:18][cH:19][cH:20]2)[CH2:3][CH2:4][N:5]([C:8]([O:9][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[CH2:6][CH2:7]1>>[OH:1][C:2]1([c:15]2[c:16]([C:21]([F:22])([F:23])[F:24])[cH:17][cH:18][cH:19][cH:20]2)[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 49760255tert-Butyl 4-hydroxy-4-[2-(trifluoromethyl)phenyl]piperidine-1-carboxylate

Product 1

HCID 226370654-[2-(Trifluoromethyl)phenyl]piperidin-4-ol

Sources & evidence

ORD record
ord-8d9f3cce599c43fdbf38aab6b8e8d9cc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…