Diisopropylethylamine → Tert-butyl 2-(4-bromo-1,3-thiazol-2-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

HRID 2329539Notes

Reaction equation

HRID 2329539 reaction equation
[Br:16][c:17]1[s:18][cH:19][c:20]([Br:22])[n:21]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]2[CH2:11][NH:12][CH2:13][CH:14]2[CH2:15]1.[CH:23]([N:24]([CH2:25][CH3:26])[CH:27]([CH3:28])[CH3:29])([CH3:30])[CH3:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]2[CH2:11][N:12]([c:17]3[s:18][cH:19][c:20]([Br:22])[n:21]3)[CH2:13][CH:14]2[CH2:15]1

Participants

4

Reactant 3

HCID 81531DiisopropylethylamineHCID 27632972,4-Dibromo-1,3-thiazoleHCID 4142526Tert-butyl octahydropyrrolo(3,4-c)pyrrole-2-carboxylate

Product 1

HCID 66846940Tert-butyl 2-(4-bromo-1,3-thiazol-2-yl)-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

Sources & evidence

ORD record
ord-f1bd8313dfc946bab54c8c34e58a7809
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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