Tetrahydrofuran → 2-[1-(3-chloro-2-pyridinyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxy-5-hydroxy-N-(5-methyl-2-pyridinyl)pentanamide
Reaction equation
[C:19]([Si:20]([CH3:21])([CH3:22])[O:24][CH2:25][CH2:26][CH2:27][CH:28]([C:29](=[O:30])[NH:31][c:32]1[n:33][cH:34][c:35]([CH3:38])[cH:36][cH:37]1)[O:39][c:40]1[c:41]2[c:42]([n:43][cH:44][n:45]1)[n:46](-[c:49]1[n:50][cH:51][cH:52][cH:53][c:54]1[Cl:55])[n:47][cH:48]2)([CH3:23])([CH3:56])[CH3:57].[CH2:58]1[O:59][CH2:60][CH2:61][CH2:62]1.[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[F-:1]>>[OH:24][CH2:25][CH2:26][CH2:27][CH:28]([C:29](=[O:30])[NH:31][c:32]1[n:33][cH:34][c:35]([CH3:38])[cH:36][cH:37]1)[O:39][c:40]1[c:41]2[c:42]([n:43][cH:44][n:45]1)[n:46](-[c:49]1[n:50][cH:51][cH:52][cH:53][c:54]1[Cl:55])[n:47][cH:48]2Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-cb9e538ed909454aa638af03f3ff7540
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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