Dichloromethane → [1-[4-[(3-Cyanonaphthalene-1-carbonyl)-methylamino]-3-(3,4-dichlorophenyl)butyl]azetidin-3-yl] methanesulfonate

HRID 2329816Notes

Reaction equation

HRID 2329816 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][c:5]([C:13](=[O:14])[N:15]([CH3:16])[CH2:17][CH:18]([CH2:19][CH2:20][N:21]2[CH2:22][CH:23]([OH:25])[CH2:24]2)[c:26]2[cH:27][c:28]([Cl:33])[c:29]([Cl:32])[cH:30][cH:31]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]2[cH:12]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[CH3:41][S:42]([Cl:43])(=[O:44])=[O:45].[Cl:46][CH2:47][Cl:48]>>[C:1](#[N:2])[c:3]1[cH:4][c:5]([C:13](=[O:14])[N:15]([CH3:16])[CH2:17][CH:18]([CH2:19][CH2:20][N:21]2[CH2:22][CH:23]([O:25][S:42]([CH3:41])(=[O:44])=[O:45])[CH2:24]2)[c:26]2[cH:27][c:28]([Cl:33])[c:29]([Cl:32])[cH:30][cH:31]2)[c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]2[cH:12]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 1784835153-cyano-N-[2-(3,4-dichlorophenyl)-4-(3-hydroxyazetidin-1-yl)butyl]-N-methylnaphthalene-1-carboxamide

Product 1

HCID 72390795[1-[4-[(3-Cyanonaphthalene-1-carbonyl)-methylamino]-3-(3,4-dichlorophenyl)butyl]azetidin-3-yl] methanesulfonate

Sources & evidence

ORD record
ord-68686a24c5d54494a8d07b1b650b921b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…