1-(2-Fluorophenyl)piperazine → 1-(3-(5-(4-chlorophenyl)-1-phenyl-1H-pyrazol-3-yl)propyl)-4-(2-fluorophenyl)piperazine
Reaction equation
[CH:36]([N:37]([CH2:38][CH3:39])[CH:40]([CH3:41])[CH3:42])([CH3:43])[CH3:44].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([CH2:19][CH2:20][CH:21]=[O:22])[n:11][n:12]2-[c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[cH:6][cH:7]1.[F:23][c:24]1[c:25]([N:30]2[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]2)[cH:26][cH:27][cH:28][cH:29]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([CH2:19][CH2:20][CH2:21][N:33]3[CH2:32][CH2:31][N:30]([c:25]4[c:24]([F:23])[cH:29][cH:28][cH:27][cH:26]4)[CH2:35][CH2:34]3)[n:11][n:12]2-[c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-3b765c98d3904ecfa031679001830aeb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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