Acetone → 4-{1-[Bis(2-chlorophenyl)-methyl)-piperidin-4-yl}-butyronitrile
Reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[C:2](#[N:3])[CH2:4][CH2:5][CH2:6][CH:7]1[CH2:8][CH2:9][NH:10][CH2:11][CH2:12]1.[CH3:35][C:36](=[O:37])[CH3:38].[Cl:13][c:14]1[c:15]([CH:20]([Br:21])[c:22]2[c:23]([Cl:28])[cH:24][cH:25][cH:26][cH:27]2)[cH:16][cH:17][cH:18][cH:19]1.[ClH:1].[K+:33].[K+:34]>>[C:2](#[N:3])[CH2:4][CH2:5][CH2:6][CH:7]1[CH2:8][CH2:9][N:10]([CH:20]([c:15]2[c:14]([Cl:13])[cH:19][cH:18][cH:17][cH:16]2)[c:22]2[c:23]([Cl:28])[cH:24][cH:25][cH:26][cH:27]2)[CH2:11][CH2:12]1Participants
7
Sources & evidence
- ORD record
- ord-70dfb1e6e49a49a4b8491d1e7afb8dec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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