Acetone → 6-(4-Fluorobenzyl)-4-methoxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carbonyl azide
Reaction equation
[CH3:30][C:31](=[O:32])[CH3:33].[F:5][c:6]1[cH:7][cH:8][c:9]([CH2:10][N:11]2[C:12](=[O:26])[c:13]3[c:14]([O:24][CH3:25])[cH:15][n:16][c:17]([C:21](=[O:22])[Cl:23])[c:18]3[CH2:19][CH2:20]2)[cH:27][cH:28]1.[N-:2]=[N+:3]=[N-:4].[Na+:1].[OH2:29]>>[N:2](=[N+:3]=[N-:4])[C:21]([c:17]1[n:16][cH:15][c:14]([O:24][CH3:25])[c:13]2[c:18]1[CH2:19][CH2:20][N:11]([CH2:10][c:9]1[cH:8][cH:7][c:6]([F:5])[cH:28][cH:27]1)[C:12]2=[O:26])=[O:22]Participants
6
Sources & evidence
- ORD record
- ord-13472b3dca0b4cbbb9f0df1b6ae00718
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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