Sodium ion → 3-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxymethyl]-phenyl}-propionic acid methyl ester

HRID 2330455Notes

Reaction equation

HRID 2330455 reaction equation
[CH3:19][O:20][C:21]([CH2:22][CH2:23][c:24]1[c:25]([CH3:32])[cH:26][c:27]([CH2:30][OH:31])[cH:28][cH:29]1)=[O:33].[H-:34].[I:1][CH2:2][c:3]1[c:4]([CH3:18])[n:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)[s:7]1.[Na+:35].[O:36]=[CH:37][N:38]([CH3:39])[CH3:40]>>[CH2:2]([c:3]1[c:4]([CH3:18])[n:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]2)[s:7]1)[O:31][CH2:30][c:27]1[cH:26][c:25]([CH3:32])[c:24]([CH2:23][CH2:22][C:21]([O:20][CH3:19])=[O:33])[cH:29][cH:28]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 6228DimethylformamideHCID 166653HydrideHCID 236145065-(Iodomethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazoleHCID 574319763-(4-Hydroxymethyl-2-methyl-phenyl)-propionic Acid Methyl Ester

Product 1

HCID 694701053-{2-Methyl-4-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxymethyl]-phenyl}-propionic acid methyl ester

Sources & evidence

ORD record
ord-754d60ba6ceb44e1b45ef46161c48678
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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