HRID2330595

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID260

Hydrogen Bromide

BrH

HCID620683

2-Amino-4-(4-bromophenyl)thiazole

C9H7BrN2S

HCID11258289

未命名化合物

PRODUCTS

产物

HCID10072721

N-[4'-(2-Amino-4-thiazolyl)-6-methyl-[1,1'-biphenyl]-3-yl]-2-(1-pyrrolidinyl)-4-pyridinecarboxamide

C26H25N5OS

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-e5df57c45e2f43d4840c24d8c1c76b99
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (10/10)

反应SMILES

[Br:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([NH2:14])[s:12][cH:13]2)[cH:7][cH:8]1.[BrH:1].[CH3:15][c:16]1[c:17]([B:36]2[O:37][C:38]([CH3:39])([CH3:40])[C:41]([CH3:42])([CH3:43])[O:44]2)[cH:18][c:19]([NH:22][C:23](=[O:24])[c:25]2[cH:26][c:27]([N:31]3[CH2:32][CH2:33][CH2:34][CH2:35]3)[n:28][cH:29][cH:30]2)[cH:20][cH:21]1>>[c:3]1(-[c:17]2[c:16]([CH3:15])[cH:21][cH:20][c:19]([NH:22][C:23](=[O:24])[c:25]3[cH:26][c:27]([N:31]4[CH2:32][CH2:33][CH2:34][CH2:35]4)[n:28][cH:29][cH:30]3)[cH:18]2)[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([NH2:14])[s:12][cH:13]2)[cH:7][cH:8]1