Dichloromethane → 1-Cyclobutylpiperazine

HRID 2330924Notes

Reaction equation

HRID 2330924 reaction equation
[CH:8]1([N:12]2[CH2:13][CH2:14][N:15]([C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[CH2:16][CH2:17]2)[CH2:9][CH2:10][CH2:11]1.[Cl:25][CH2:26][Cl:27].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[CH:8]1([N:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[CH2:9][CH2:10][CH2:11]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 57423951Tert-butyl 4-cyclobutylpiperazine-1-carboxylate

Product 1

HCID 47386021-Cyclobutylpiperazine

Sources & evidence

ORD record
ord-a5431a305b8245479fcd3c31b9da72b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…