Imidazole → HCID 178453051, compound

HRID 2331080Notes

Reaction equation

HRID 2331080 reaction equation
[C:29]([CH3:30])([CH3:31])([CH3:32])[Si:33]([CH3:34])([CH3:35])[Cl:36].[O:37]=[CH:38][N:39]([CH3:40])[CH3:41].[OH:1][CH:2]([CH:3]([c:4]1[cH:5][cH:6][c:7]([C:10]([F:11])([F:12])[F:13])[cH:8][cH:9]1)[NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:22][OH:23].[nH:24]1[cH:25][cH:26][n:27][cH:28]1>>[OH:1][CH:2]([CH:3]([c:4]1[cH:5][cH:6][c:7]([C:10]([F:11])([F:12])[F:13])[cH:8][cH:9]1)[NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:22][O:23][Si:33]([C:29]([CH3:30])([CH3:31])[CH3:32])([CH3:34])[CH3:35]

Participants

5

Reactant 4

HCID 795ImidazoleHCID 6228DimethylformamideHCID 28928tert-Butyldimethylsilyl chlorideHCID 76571202tert-butyl N-[2,3-dihydroxy-1-[4-(trifluoromethyl)phenyl]propyl]carbamate

Product 1

HCID 178453051HCID 178453051, compound

Sources & evidence

ORD record
ord-8b97938efa1443b5aa75ab77ad13ebc8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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