Dichloromethane → 6-[4-(3,3-dimethyl-butyryl)-piperazin-1-yl]-N-(3-iodo-4-methyl-phenyl)-nicotinamide
Reaction equation
[CH3:1][C:2]([CH2:3][C:4](=[O:5])[Cl:6])([CH3:7])[CH3:8].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[Cl:32][CH2:33][Cl:34].[I:9][c:10]1[cH:11][c:12]([NH:17][C:18]([c:19]2[cH:20][n:21][c:22]([N:25]3[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]3)[cH:23][cH:24]2)=[O:31])[cH:13][cH:14][c:15]1[CH3:16]>>[CH3:1][C:2]([CH2:3][C:4](=[O:5])[N:28]1[CH2:27][CH2:26][N:25]([c:22]2[n:21][cH:20][c:19]([C:18]([NH:17][c:12]3[cH:11][c:10]([I:9])[c:15]([CH3:16])[cH:14][cH:13]3)=[O:31])[cH:24][cH:23]2)[CH2:30][CH2:29]1)([CH3:7])[CH3:8]Participants
5
Sources & evidence
- ORD record
- ord-79d6d337918942ab9113df0095cf9fda
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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