Nitric Acid → Ethyl 5-methoxy-4-((1-methylpiperidin-4-yl)methoxy)-2-nitrobenzoate

HRID 2331483Notes

Reaction equation

HRID 2331483 reaction equation
[CH3:8][O:9][c:10]1[cH:11][c:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[cH:18][cH:19][c:20]1[O:21][CH2:22][CH:23]1[CH2:24][CH2:25][N:26]([CH3:29])[CH2:27][CH2:28]1.[Cl:34][CH2:35][Cl:36].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7].[OH:30][N+:31]([O-:32])=[O:33]>>[CH3:8][O:9][c:10]1[cH:11][c:12]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[c:18]([N+:31](=[O:30])[O-:32])[cH:19][c:20]1[O:21][CH2:22][CH:23]1[CH2:24][CH2:25][N:26]([CH3:29])[CH2:27][CH2:28]1

Participants

5

Reactant 4

HCID 944Nitric AcidHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 21874826Ethyl 3-methoxy-4-((1-methylpiperidin-4-yl)methoxy)benzoate

Product 1

HCID 21874808Ethyl 5-methoxy-4-((1-methylpiperidin-4-yl)methoxy)-2-nitrobenzoate

Sources & evidence

ORD record
ord-8211a8cbad594792a9408bf13be4f526
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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