Hydrochloric Acid → 7-[2-(4-Methyl-piperazin-1-yl)-pyrimidin-5-yl]-3-(4-nitro-phenyl)-imidazo[1,2-a]pyridine

HRID 2331699Notes

Reaction equation

HRID 2331699 reaction equation
[Br:28][c:29]1[cH:30][n:31][c:32]([N:35]2[CH2:36][CH2:37][N:38]([CH3:41])[CH2:39][CH2:40]2)[n:33][cH:34]1.[C:43](=[O:44])([O-:45])[O-:46].[CH2:49]1[O:50][CH2:51][CH2:52][O:53][CH2:54]1.[ClH:42].[K+:47].[K+:48].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7](-[c:10]2[cH:11][n:12][c:13]3[n:14]2[cH:15][cH:16][c:17]([B:19]2[O:20][C:21]([CH3:22])([CH3:23])[C:24]([CH3:25])([CH3:26])[O:27]2)[cH:18]3)[cH:8][cH:9]1.[OH2:55]>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7](-[c:10]2[cH:11][n:12][c:13]3[n:14]2[cH:15][cH:16][c:17](-[c:29]2[cH:30][n:31][c:32]([N:35]4[CH2:36][CH2:37][N:38]([CH3:41])[CH2:39][CH2:40]4)[n:33][cH:34]2)[cH:18]3)[cH:8][cH:9]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 41281585-Bromo-2-(4-methylpiperazin-1-yl)pyrimidineHCID 68543262HCID 68543262, compound

Product 1

HCID 685412717-[2-(4-Methyl-piperazin-1-yl)-pyrimidin-5-yl]-3-(4-nitro-phenyl)-imidazo[1,2-a]pyridine

Sources & evidence

ORD record
ord-23b7b9f2bcf6485688993deaf7485bcf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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