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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2332232Generated: October 30, 2026

Tetrahydrofuran → 2-{(SR)-1-[(3SR,4SR)-1-Benzyl-3-(4-chloro-phenyl)-piperidin-4-yl]-ethoxy}-5-chloro-pyridine

https://huagongshe.com/reaction/2332232

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantDi-tert-butyl azodicarboxylateHCID 97268—
Reactant(RS)-1-[(3SR,4SR)-1-Benzyl-3-(4-chloro-phenyl)-piperidin-4-yl]-ethanolHCID 68475389—
Reactant5-chloropyridin-2-olHCID 178516064—
Product2-{(SR)-1-[(3SR,4SR)-1-Benzyl-3-(4-chloro-phenyl)-piperidin-4-yl]-ethoxy}-5-chloro-pyridineHCID 68471556—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-8b3d57cddb864cc9938e35b6b14902b3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)