Tetrahydrofuran → 2-{(SR)-1-[(3SR,4SR)-1-Benzyl-3-(4-chloro-phenyl)-piperidin-4-yl]-ethoxy}-5-chloro-pyridine
Reaction equation
[CH2:44]([c:45]1[cH:46][cH:47][cH:48][cH:49][cH:50]1)[N:51]1[CH2:52][CH:53]([c:60]2[cH:61][cH:62][c:63]([Cl:66])[cH:64][cH:65]2)[CH:54]([CH:57]([CH3:58])[OH:59])[CH2:55][CH2:56]1.[CH2:67]1[O:68][CH2:69][CH2:70][CH2:71]1.[Cl:36][c:37]1[cH:38][cH:39][c:40]([OH:43])[n:41][cH:42]1.[N:20]([C:21]([O:22][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:27])=[N:28][C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[Cl:36][c:37]1[cH:38][cH:39][c:40]([O:43][CH:57]([CH:54]2[CH:53]([c:60]3[cH:61][cH:62][c:63]([Cl:66])[cH:64][cH:65]3)[CH2:52][N:51]([CH2:44][c:45]3[cH:46][cH:47][cH:48][cH:49][cH:50]3)[CH2:56][CH2:55]2)[CH3:58])[n:41][cH:42]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-8b3d57cddb864cc9938e35b6b14902b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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