Toluene → 4-(4-Chloro-2-fluorophenoxy)-7-hydroxy-6-methoxyquinazoline
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:28][CH3:29])[cH:11][c:12]2[c:13]([O:19][c:20]3[c:21]([F:27])[cH:22][c:23]([Cl:26])[cH:24][cH:25]3)[n:14][cH:15][n:16][c:17]2[cH:18]1.[CH3:37][c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1.[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[OH:8][c:9]1[c:10]([O:28][CH3:29])[cH:11][c:12]2[c:13]([O:19][c:20]3[c:21]([F:27])[cH:22][c:23]([Cl:26])[cH:24][cH:25]3)[n:14][cH:15][n:16][c:17]2[cH:18]1Participants
4
Sources & evidence
- ORD record
- ord-cb7ec0ca2c46427188aecfdfe7d03dcc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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