Dichloromethane → 2-Amino-1-[4-(3,4-dichlorophenoxy)-piperidine-1-yl]-3-methyl-butan-1-one
Reaction equation
[Cl:1][c:2]1[cH:3][c:4]([O:5][CH:6]2[CH2:7][CH2:8][N:9]([C:12](=[O:13])[CH:14]([CH:15]([CH3:16])[CH3:17])[NH:18][C:19](=[O:20])[CH3:21])[CH2:10][CH2:11]2)[cH:22][cH:23][c:24]1[Cl:25].[Cl:33][CH2:34][Cl:35].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[Cl:1][c:2]1[cH:3][c:4]([O:5][CH:6]2[CH2:7][CH2:8][N:9]([C:12](=[O:13])[CH:14]([CH:15]([CH3:16])[CH3:17])[NH2:18])[CH2:10][CH2:11]2)[cH:22][cH:23][c:24]1[Cl:25]Participants
4
Sources & evidence
- ORD record
- ord-3fdd3df240c8416eb3e0885dc51ee4e3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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