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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2332809Generated: October 26, 2026

Nitrogen → N-(4-(1-(4-methoxybenzyl)-3-(5-((4-methylpiperazin-1-yl)methyl)furan-3-yl)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

https://huagongshe.com/reaction/2332809

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitrogenHCID 947—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 68512093HCID 68512093—
Reactant1-((4-Bromo-5-(tributylstannyl)furan-2-yl)methyl)-4-methylpiperazineHCID 68512181—
Reactant1-Methyl-4-((4-(tributylstannyl)furan-2-yl)methyl)piperazineHCID 68513247—
ProductN-(4-(1-(4-methoxybenzyl)-3-(5-((4-methylpiperazin-1-yl)methyl)furan-3-yl)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorophenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamideHCID 68512150—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-704c93a289da4b7aaa1ee0aeec52ef7c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)