Dimethylformamide → Methyl 6-{4-[({5-[(2-fluorophenyl)amino]-1,3,4-oxadiazol-2-yl}carbonyl)amino]-piperidin-1-yl}nicotinate

HRID 2332882Notes

Reaction equation

HRID 2332882 reaction equation
[Cl:23][c:24]1[n:25][cH:26][c:27]([C:28](=[O:29])[O:30][CH3:31])[cH:32][cH:33]1.[F:1][c:2]1[c:3]([NH:8][c:9]2[n:10][n:11][c:12]([C:14](=[O:15])[NH:16][CH:17]3[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]3)[o:13]2)[cH:4][cH:5][cH:6][cH:7]1.[O:34]=[CH:35][N:36]([CH3:37])[CH3:38]>>[F:1][c:2]1[c:3]([NH:8][c:9]2[n:10][n:11][c:12]([C:14](=[O:15])[NH:16][CH:17]3[CH2:18][CH2:19][N:20]([c:24]4[n:25][cH:26][c:27]([C:28](=[O:29])[O:30][CH3:31])[cH:32][cH:33]4)[CH2:21][CH2:22]3)[o:13]2)[cH:4][cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 254249Methyl 6-chloropyridine-3-carboxylateHCID 594641305-[(2-fluorophenyl)amino]-N-piperidin-4-yl-1,3,4-oxadiazole-2-carboxamide

Product 1

HCID 59464313Methyl 6-{4-[({5-[(2-fluorophenyl)amino]-1,3,4-oxadiazol-2-yl}carbonyl)amino]-piperidin-1-yl}nicotinate

Sources & evidence

ORD record
ord-56f4a045df5547bd94935f3082848770
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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