N-methyl-2-pyrrolidone → 5-(2-Fluoro-phenoxy)-2-pyrazin-2-yl-6-(6-trifluoromethyl-pyridin-3-yloxy)-1H-benzimidazole
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[n:6][cH:7]1.[C:12](=[O:13])([O-:14])[O-:15].[CH3:42][N:43]1[CH2:44][CH2:45][CH2:46][C:47]1=[O:48].[Cs+:16].[Cs+:17].[F:18][c:19]1[c:20]([O:21][c:22]2[cH:23][c:24]3[c:25]([nH:26][c:27](-[c:29]4[n:30][cH:31][cH:32][n:33][cH:34]4)[n:28]3)[cH:35][c:36]2[OH:37])[cH:38][cH:39][cH:40][cH:41]1>>[c:2]1([O:37][c:36]2[c:22]([O:21][c:20]3[c:19]([F:18])[cH:41][cH:40][cH:39][cH:38]3)[cH:23][c:24]3[c:25]([nH:26][c:27](-[c:29]4[n:30][cH:31][cH:32][n:33][cH:34]4)[n:28]3)[cH:35]2)[cH:3][cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[n:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-eaab25e9928545edb9d2165e908011fa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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