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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2333028Generated: October 27, 2026

Tetrahydrofuran → Ethyl 2-methyl-2-[4-(2-{[5-(2,2,2-trifluoro-1-hydroxyethyl)pyridin-2-yl][4-(trifluoromethoxy)benzyl]amino}ethyl)phenoxy]propanoate

https://huagongshe.com/reaction/2333028

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant(Trifluoromethyl)trimethylsilaneHCID 552549—
ReactantEthyl 2-[4-(2-{(5-formylpyridin-2-yl)[4-(trifluoromethoxy)benzyl]amino}ethyl)phenoxy]-2-methylpropanoateHCID 59643273—
ProductEthyl 2-methyl-2-[4-(2-{[5-(2,2,2-trifluoro-1-hydroxyethyl)pyridin-2-yl][4-(trifluoromethoxy)benzyl]amino}ethyl)phenoxy]propanoateHCID 86598931—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-95802a24d05c488b99f46451091f9829
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)