Tetrahydrofuran → Ethyl 2-methyl-2-[4-(2-{[5-(2,2,2-trifluoro-1-hydroxyethyl)pyridin-2-yl][4-(trifluoromethoxy)benzyl]amino}ethyl)phenoxy]propanoate
Reaction equation
[CH2:65]1[O:66][CH2:67][CH2:68][CH2:69]1.[CH3:48][CH2:49][CH2:50][CH2:51][N+:52]([CH2:53][CH2:54][CH2:55][CH3:56])([CH2:57][CH2:58][CH2:59][CH3:60])[CH2:61][CH2:62][CH2:63][CH3:64].[CH:1](=[O:2])[c:3]1[cH:4][cH:5][c:6]([N:9]([CH2:10][CH2:11][c:12]2[cH:13][cH:14][c:15]([O:16][C:17]([C:18](=[O:19])[O:20][CH2:21][CH3:22])([CH3:23])[CH3:24])[cH:25][cH:26]2)[CH2:27][c:28]2[cH:29][cH:30][c:31]([O:34][C:35]([F:36])([F:37])[F:38])[cH:32][cH:33]2)[n:7][cH:8]1.[F-:47].[F:39][C:40]([F:41])([F:42])[Si:43]([CH3:44])([CH3:45])[CH3:46]>>[CH:1]([OH:2])([c:3]1[cH:4][cH:5][c:6]([N:9]([CH2:10][CH2:11][c:12]2[cH:13][cH:14][c:15]([O:16][C:17]([C:18](=[O:19])[O:20][CH2:21][CH3:22])([CH3:23])[CH3:24])[cH:25][cH:26]2)[CH2:27][c:28]2[cH:29][cH:30][c:31]([O:34][C:35]([F:36])([F:37])[F:38])[cH:32][cH:33]2)[n:7][cH:8]1)[C:40]([F:39])([F:41])[F:42]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-95802a24d05c488b99f46451091f9829
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…