Tetrahydrofuran → tert-Butyl 4-hydroxy-2-methylpyrrolidine-1-carboxylate

HRID 2333150Notes

Reaction equation

HRID 2333150 reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH:7]1[CH2:8][CH:9]([CH3:19])[N:10]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:11]1)([CH3:5])([CH3:20])[CH3:21].[CH3:23][CH2:24][CH2:25][CH2:26][N+:27]([CH2:28][CH2:29][CH2:30][CH3:31])([CH2:32][CH2:33][CH2:34][CH3:35])[CH2:36][CH2:37][CH2:38][CH3:39].[F-:22].[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1>>[OH:6][CH:7]1[CH2:8][CH:9]([CH3:19])[N:10]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:11]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 19900185HCID 19900185, compound

Product 1

HCID 14117009tert-Butyl 4-hydroxy-2-methylpyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-d068f17f5a884c35a9da306464a7b87d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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