Hydroxide → 1-(4-(2-Fluoropyridin-3-yl)piperidin-1-yl)ethanone

HRID 2333161Notes

Reaction equation

HRID 2333161 reaction equation
[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1[C:8]1=[CH:9][CH2:10][N:11]([C:14]([CH3:15])=[O:16])[CH2:12][CH2:13]1.[OH-:17].[OH-:19].[Pd+2:18]>>[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1[CH:8]1[CH2:9][CH2:10][N:11]([C:14]([CH3:15])=[O:16])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 961Hydroxide2×HCID 8028TetrahydrofuranHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 593269651-(4-(2-fluoropyridin-3-yl)-5,6-dihydropyridin-1(2H)-yl)ethanone

Product 1

HCID 585478341-(4-(2-Fluoropyridin-3-yl)piperidin-1-yl)ethanone

Sources & evidence

ORD record
ord-09017e09376c4cd3afacf455a677f979
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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