Water → 3'-Chloro-4'-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-biphenyl-4-carboxylic acid methyl ester
Reaction equation
[CH3:31][O:32][C:33](=[O:34])[c:35]1[cH:36][cH:37][c:38]([B:41]([OH:42])[OH:43])[cH:39][cH:40]1.[CH3:51][CH2:52][O:53][C:54](=[O:55])[CH3:56].[Cl:1][c:2]1[cH:3][c:4]([O:23][S:24]([C:25]([F:26])([F:27])[F:28])(=[O:29])=[O:30])[cH:5][cH:6][c:7]1[CH:8]([C:9]([C:10]([F:11])([F:12])[F:13])([OH:14])[c:15]1[cH:16][c:17]([Cl:21])[n:18][cH:19][cH:20]1)[CH3:22].[O:45]1[CH2:46][CH2:47][O:48][CH2:49][CH2:50]1.[OH2:44]>>[Cl:1][c:2]1[cH:3][c:4](-[c:38]2[cH:37][cH:36][c:35]([C:33]([O:32][CH3:31])=[O:34])[cH:40][cH:39]2)[cH:5][cH:6][c:7]1[CH:8]([C:9]([C:10]([F:11])([F:12])[F:13])([OH:14])[c:15]1[cH:16][c:17]([Cl:21])[n:18][cH:19][cH:20]1)[CH3:22]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d3faa8b45c414f1085b1f0a640faf885
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…