Acetate → 4-(5-(1-Ethoxyvinyl)-2-fluoropyridin-3-YL)-6-methyl-1,3,5-triazin-2-amine

HRID 2333455Notes

Reaction equation

HRID 2333455 reaction equation
[CH2:24]([Sn:25]([CH2:26][CH2:27][CH2:28][CH3:34])([C:29](=[CH2:30])[O:31][CH2:32][CH3:33])[CH2:35][CH2:36][CH2:37][CH3:38])[CH2:39][CH2:40][CH3:41].[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]([NH2:16])[n:12][c:13]([CH3:15])[n:14]2)[c:5]([F:8])[n:6][cH:7]1.[Cs+:23].[F-:22].[O-:43][C:44]([CH3:45])=[O:46].[O-:47][C:48]([CH3:49])=[O:50].[O:17]=[CH:18][N:19]([CH3:20])[CH3:21].[O:51]1[CH2:52][CH2:53][O:54][CH2:55][CH2:56]1.[Pd+2:42]>>[c:2]1([C:29](=[CH2:30])[O:31][CH2:32][CH3:33])[cH:3][c:4](-[c:9]2[n:10][c:11]([NH2:16])[n:12][c:13]([CH3:15])[n:14]2)[c:5]([F:8])[n:6][cH:7]1

Participants

9

Reactant 8

HCID 175Acetate2×HCID 6228DimethylformamideHCID 28179Fluoride IonHCID 312751,4-DioxaneHCID 104967Cesium cationHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 619414Stannane, tributyl(1-ethoxyethenyl)-HCID 666118184-(5-Chloro-2-fluoropyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine

Product 1

HCID 666118404-(5-(1-Ethoxyvinyl)-2-fluoropyridin-3-YL)-6-methyl-1,3,5-triazin-2-amine

Sources & evidence

ORD record
ord-1ce2a202260f41c3836d9b7c2053a0c0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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