Methanol → 4-Nitro-2-(5-hydroxy-2,6-dioxopiperid-3-yl)isoindoline-1-one

HRID 2333843Notes

Reaction equation

HRID 2333843 reaction equation
[CH3:37][OH:38].[N+:1](=[O:2])([O-:3])[c:4]1[c:5]2[c:9]([cH:10][cH:11][cH:12]1)[C:8](=[O:13])[N:7]([CH:14]1[C:15](=[O:25])[NH:16][C:17](=[O:24])[CH:18]([O:20][C:21](=[O:22])[CH3:23])[CH2:19]1)[CH2:6]2.[c:26]1([CH3:27])[cH:28][cH:29][c:30]([S:31]([OH:32])(=[O:33])=[O:34])[cH:35][cH:36]1>>[N+:1](=[O:2])([O-:3])[c:4]1[c:5]2[c:9]([cH:10][cH:11][cH:12]1)[C:8](=[O:13])[N:7]([CH:14]1[C:15](=[O:25])[NH:16][C:17](=[O:24])[CH:18]([OH:20])[CH2:19]1)[CH2:6]2

Participants

4

Reactant 3

HCID 887MethanolHCID 6101p-Toluenesulfonic acidHCID 222411953-(4-Nitro-1-oxoisoindolin-2-yl)-2,6-dioxo-5-acetoxypiperidine

Product 1

HCID 222412004-Nitro-2-(5-hydroxy-2,6-dioxopiperid-3-yl)isoindoline-1-one

Sources & evidence

ORD record
ord-7f8aff3e0d144272a2c710f060f32bdf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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