Dimethyl Sulfoxide → tert-Butyl 2-formylpiperidine-1-carboxylate

HRID 2333899Notes

Reaction equation

HRID 2333899 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:14][OH:15])[CH2:10][CH2:11][CH2:12][CH2:13]1.[CH3:22][S:23]([CH3:24])=[O:25].[Cl:16][C:17]([C:18]([Cl:19])=[O:20])=[O:21]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:14]=[O:15])[CH2:10][CH2:11][CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 65578Oxalyl chlorideHCID 2763853N-Boc-piperidine-2-methanol

Product 1

HCID 10656219tert-Butyl 2-formylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-1c38bf4af9024edca7264f7aba8bafae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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