o-Xylyl bromide → Dimethyl [(2-methylphenyl)methyl]phosphonate
Reaction equation
F[C:2]1[CH:14]=[CH:13][C:5]([CH2:6][P:7](=[O:12])([O:10][CH3:11])[O:8][CH3:9])=[CH:4][CH:3]=1.[CH3:15]C1C=CC=CC=1CBr.COP(OC)OC>>[CH3:15][C:13]1[CH:14]=[CH:2][CH:3]=[CH:4][C:5]=1[CH2:6][P:7](=[O:12])([O:10][CH3:11])[O:8][CH3:9]Participants
4
Procedure
Following the procedure of Compound 11, 2-methylbenzyl bromide is reacted with trimethylphosphite.
Sources & evidence
- ORD record
- ord-bef605dbeab649e5b17d3c663ba6b42d
- Source dataset
- uspto-grants-1997_01
- Patent number
- US05593980
Reaction notes
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