Trifluoroacetic acid → (5-(4-Amino-6-methyl-1,3,5-triazin-2-yl)-6-(5-fluoro-6-methoxypyridin-3-ylamino)pyridin-3-yl)(4-hydroxypiperidin-1-yl)methanone

HRID 2334415Notes

Reaction equation

HRID 2334415 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][N:8]([c:9]2[n:10][c:11](-[c:16]3[cH:17][c:18]([C:32](=[O:33])[N:34]4[CH2:35][CH2:36][CH:37]([OH:40])[CH2:38][CH2:39]4)[cH:19][n:20][c:21]3[NH:22][c:23]3[cH:24][n:25][c:26]([O:30][CH3:31])[c:27]([F:29])[cH:28]3)[n:12][c:13]([CH3:15])[n:14]2)[CH2:41][c:42]2[cH:43][cH:44][c:45]([O:46][CH3:47])[cH:48][cH:49]2)[cH:50][cH:51]1.[F:52][C:53]([F:54])([F:55])[C:56]([OH:57])=[O:58]>>[NH2:8][c:9]1[n:10][c:11](-[c:16]2[cH:17][c:18]([C:32](=[O:33])[N:34]3[CH2:35][CH2:36][CH:37]([OH:40])[CH2:38][CH2:39]3)[cH:19][n:20][c:21]2[NH:22][c:23]2[cH:24][n:25][c:26]([O:30][CH3:31])[c:27]([F:29])[cH:28]2)[n:12][c:13]([CH3:15])[n:14]1

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 66611784(5-(4-(Bis(4-methoxybenzyl)amino)-6-methyl-1,3,5-triazin-2-YL)-6-(5-fluoro-6-methoxypyridin-3-ylamino)pyridin-3-YL)(4-hydroxypiperidin-1-YL)methanone

Product 1

HCID 59548438(5-(4-Amino-6-methyl-1,3,5-triazin-2-yl)-6-(5-fluoro-6-methoxypyridin-3-ylamino)pyridin-3-yl)(4-hydroxypiperidin-1-yl)methanone

Sources & evidence

ORD record
ord-ad213fb4e1bd4ac09be4177edc4be8eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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