Dichloromethane → 2-phenyl-1,3,8-Triazaspiro[4.5]dec-1-en-4-one

HRID 2334509Notes

Reaction equation

HRID 2334509 reaction equation
[Cl:32][CH2:33][Cl:34].[O:1]=[C:2]1[NH:3][C:4]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)=[N:5][C:6]12[CH2:7][CH2:8][N:9]([C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH2:10][CH2:11]2.[OH:25][C:26]([C:27]([F:28])([F:29])[F:30])=[O:31]>>[O:1]=[C:2]1[NH:3][C:4]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)=[N:5][C:6]12[CH2:7][CH2:8][NH:9][CH2:10][CH2:11]2

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 59165778Tert-butyl 4-oxo-2-phenyl-1,3,8-triazaspiro[4.5]dec-1-ene-8-carboxylate

Product 1

HCID 211021472-phenyl-1,3,8-Triazaspiro[4.5]dec-1-en-4-one

Sources & evidence

ORD record
ord-b0b1f1059b2f4016a1b38682fcc7e62f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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