Hydrochloric Acid → HCID 23356470, compound

Participants

Reaction Steps

To 2.0 g of 6-cyano-1-methylpyrrolo[1,2-a]pyrazine prepared in Preparation Example 4 were added 10 ml of water and 5 ml of hydrochloric acid; and the reaction mixture was reacted at 80° C. for 2 hours, cooled to room temperature, extracted with ethyl acetate, and concentrated. The residue was chromatographed over silica gel to obtain 1.0 g of title compound.

Provenance & Evidence