Sodium ion → 5-fluoro-2'-[3-iodo-1-(2-trimethylsilylethoxymethyl)indazol-6-yl]spiro[1H-indole-3,1'-cyclopropane]-2-one
Reaction equation
[CH3:2][S+:3]([CH3:4])([CH3:5])=[O:6].[F:9][c:10]1[cH:11][c:12]2[c:16]([cH:17][cH:18]1)[NH:15][C:14](=[O:19])[C:13]2=[CH:20][c:21]1[cH:22][cH:23][c:24]2[c:25]([I:38])[n:26][n:27]([CH2:30][O:31][CH2:32][CH2:33][Si:34]([CH3:35])([CH3:36])[CH3:37])[c:28]2[cH:29]1.[H-:7].[I-:1].[Na+:8].[O:39]=[CH:40][N:41]([CH3:42])[CH3:43]>>[CH2:2]1[C:13]2([c:12]3[cH:11][c:10]([F:9])[cH:18][cH:17][c:16]3[NH:15][C:14]2=[O:19])[CH:20]1[c:21]1[cH:22][cH:23][c:24]2[c:25]([I:38])[n:26][n:27]([CH2:30][O:31][CH2:32][CH2:33][Si:34]([CH3:35])([CH3:36])[CH3:37])[c:28]2[cH:29]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-113dbcbb7f9c4dd18949a8c5c6275ac5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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