Methanesulfonic Acid → HCID 86750174, compound

Participants

Reaction Steps

A solution of methanesulfonic acid (181 mg) in ethanol (7 ml) was added to a suspension of (2β,3α,5α)-3-hydroxy-2-(2,2-dibutyl-4-morpholinyl)pregnane-11,20-dione (1.0 g) in ethanol (3 ml). The resulting suspension was heated to effect solution and the solvent was removed under reduced pressure to give (2β,3α,5α)-3-hydroxy-2-(2,2-dibutyl-4-morpholinyl)pregnane-11,20-dione methanesulfonate (1:1) salt (1.06 g). [α]D +86.3° (c 0.7).

Provenance & Evidence