Water → Tert-butyl 2-[3-acetyl-4-[(3,5-difluorophenyl)methyl]-2,2-dimethyl-1,3-oxazolidin-5-yl]-4-hydroxypyrrolidine-1-carboxylate

HRID 2335158Notes

Reaction equation

HRID 2335158 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:23]2[CH:24]([CH2:33][c:34]3[cH:35][c:36]([F:41])[cH:37][c:38]([F:40])[cH:39]3)[N:25]([C:30]([CH3:31])=[O:32])[C:26]([CH3:28])([CH3:29])[O:27]2)[CH2:10][CH:11]([O:13][CH2:14][c:15]2[cH:16][cH:17][c:18]([O:19][CH3:20])[cH:21][cH:22]2)[CH2:12]1.[Cl:42][CH2:43][Cl:44].[Cl:45][C:46]1=[C:57]([Cl:58])[C:55](=[O:56])[C:52]([C:53]#[N:54])=[C:49]([C:50]#[N:51])[C:47]1=[O:48].[OH2:59]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:23]2[CH:24]([CH2:33][c:34]3[cH:35][c:36]([F:41])[cH:37][c:38]([F:40])[cH:39]3)[N:25]([C:30]([CH3:31])=[O:32])[C:26]([CH3:28])([CH3:29])[O:27]2)[CH2:10][CH:11]([OH:13])[CH2:12]1

Participants

5

Reactant 4

HCID 962WaterHCID 6344DichloromethaneHCID 67752,3-Dichloro-5,6-dicyano-1,4-benzoquinoneHCID 178491278HCID 178491278, compound

Product 1

HCID 77558581Tert-butyl 2-[3-acetyl-4-[(3,5-difluorophenyl)methyl]-2,2-dimethyl-1,3-oxazolidin-5-yl]-4-hydroxypyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-f08961baa560451ca5c28aa3d8065c5e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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