huagongshe.com
HRID233523

反应详情

EQUATION

反应方程式

HRID 233523 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)O
HCID6395

Methanesulfonic acid

CH4O3S

结构：CC1(C)CN([C@H]2C[C@@]3(C)[C@@H](CC[C@@H]4[C@@H]3CC[C@]3(C)[C@@H](C(=O)CSC#N)CC[C@@H]43)C[C@@H]2O)CCO1
HCID53898985

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)CN([C@H]2C[C@@]3(C)[C@@H](CC[C@@H]4[C@@H]3CC[C@]3(C)[C@@H](C(=O)CSC#N)CC[C@@H]43)C[C@@H]2O)CCO1.CS(=O)(=O)O
HCID86750182

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

A solution of methanesulfonic acid (88 mg) in methanol (100 ml) was added to (2β,3α,5α)-3-hydroxy-2-(2,2-dimethyl-4-morpholinyl)-21-thiocyanatopregnan-20-one (445 mg) and the solvent was removed from the resulting solution to give (2β,3α,5α)-3-hydroxy-2-(2,2-dimethyl-4-morpholinyl)-21-thiocyanatopregnan-20-one methanesulfonate (1:1) salt (432 mg). [α]D +100.8° (c 0.4).

WORKUP

后处理

  1. customthe solvent was removed from the resulting solution