Chloride → ethyl 6-amino-2,2-bisfluoromethyl-2H-1-benzopyran-4-carboxylate

HRID 2335350Notes

Reaction equation

HRID 2335350 reaction equation
[CH2:26]([OH:27])[CH3:28].[Cl-:23].[F:1][CH2:2][C:3]1([CH2:21][F:22])[O:4][c:5]2[c:6]([cH:14][c:15]([N+:18]([O-:19])=[O:20])[cH:16][cH:17]2)[C:7]([C:9](=[O:10])[O:11][CH2:12][CH3:13])=[CH:8]1.[Na+:25].[OH-:24]>>[F:1][CH2:2][C:3]1([CH2:21][F:22])[O:4][c:5]2[c:6]([cH:14][c:15]([NH2:18])[cH:16][cH:17]2)[C:7]([C:9](=[O:10])[O:11][CH2:12][CH3:13])=[CH:8]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 19037092HCID 19037092, compound

Product 1

HCID 19037020ethyl 6-amino-2,2-bisfluoromethyl-2H-1-benzopyran-4-carboxylate

Sources & evidence

ORD record
ord-df503a85c4e2439eab21fb2d2b21070c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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