Sodium ion → 3-Methyl-1,6-diazaspiro[3,5]nonane-1-carboxylic acid 1-benzyl ester

HRID 2335448Notes

Reaction equation

HRID 2335448 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][C:10]2([CH:11]([CH3:24])[CH2:12][N:13]2[C:14](=[O:15])[O:16][CH2:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[CH2:25][CH2:26][CH2:27]1)([CH3:5])([CH3:6])[CH3:7].[CH:28]([Cl:29])([Cl:30])[Cl:31].[CH:41]([Cl:42])([Cl:43])[Cl:44].[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38].[Na+:40].[OH-:39]>>[NH:8]1[CH2:9][C:10]2([CH:11]([CH3:24])[CH2:12][N:13]2[C:14](=[O:15])[O:16][CH2:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[CH2:25][CH2:26][CH2:27]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 961HydroxideHCID 6212Chloroform2×HCID 6422Trifluoroacetic acidHCID 582933041-Benzyl6-tert-butyl3-methyl-1,6-diazaspiro[3.5]nonane-1,6-dicarboxylate

Product 1

HCID 582933243-Methyl-1,6-diazaspiro[3,5]nonane-1-carboxylic acid 1-benzyl ester

Sources & evidence

ORD record
ord-572a8b944a174c4ca39c5575fd259cf5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…