Chloride → tert-Butyl 9-hydroxy-3-azaspiro[5.5]undecane-3-carboxylate

HRID 2335486Notes

Reaction equation

HRID 2335486 reaction equation
[BH4-:31].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([CH2:12][CH2:13]1)[CH2:14][CH2:15][C:16](=[O:19])[CH2:17][CH2:18]2.[CH3:34][OH:35].[Ce+3:28].[Cl-:27].[Cl-:29].[Cl-:30].[Na+:32].[OH2:20].[OH2:21].[OH2:22].[OH2:23].[OH2:24].[OH2:25].[OH2:26].[OH2:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]2([CH2:12][CH2:13]1)[CH2:14][CH2:15][CH:16]([OH:19])[CH2:17][CH2:18]2

Participants

8

Reactant 7

HCID 312Chloride3×HCID 887MethanolHCID 923Sodium ionHCID 962Water8×HCID 28123BorohydrideHCID 114853Cerium(3+)HCID 51072194tert-Butyl 9-oxo-3-azaspiro[5.5]undecane-3-carboxylate

Product 1

HCID 66701044tert-Butyl 9-hydroxy-3-azaspiro[5.5]undecane-3-carboxylate

Sources & evidence

ORD record
ord-0fdf563fbb0c4344a5f66785386325d9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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