Dichloromethane → Tert-butyl 4-[6-(4-cyclohexyl-3-trifluoromethyl-phenoxymethyl)-pyridin-3-yl]-piperazine-1-carboxylate
Reaction equation
[CH:22]1([c:28]2[c:29]([C:35]([F:36])([F:37])[F:38])[cH:30][c:31]([OH:34])[cH:32][cH:33]2)[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]1.[Cl:58][CH2:59][Cl:60].[OH:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([N:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[cH:7][n:8]1.[c:39]1([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[cH:53][cH:54][cH:55][cH:56][cH:57]1>>[O:1]([CH2:2][c:3]1[cH:4][cH:5][c:6]([N:9]2[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[cH:7][n:8]1)[c:31]1[cH:30][c:29]([C:35]([F:36])([F:37])[F:38])[c:28]([CH:22]2[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]2)[cH:33][cH:32]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-5d7d003e6d51433f98c183401bc4c759
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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