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HRID233554

反应详情

EQUATION

反应方程式

HRID 233554 的结构方程式

REACTANTS

反应物

2
结构：[I-].[Na+]
HCID5238

Sodium Iodide

INa

结构：C=CCO[C@H]1O[C@H](COS(=O)(=O)c2ccccc2C)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]1NC(C)=O
HCID86749068

未命名化合物

PRODUCTS

生成物

1
结构：C=CCO[C@H]1O[C@H](CI)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H]1NC(C)=O
HCID15663094

未命名化合物

收率 88%

PROCEDURE

实验过程

A solution of allyl 2-acetamido-3,4-di-O-acetyl-2-deoxy-6-O-tolylsulfonyl-α-D-mannopyranoside, prepared as described above, (3.68 g, 7.37 mmol) and NaI (2.21 g, 14.7 mmol) was gently refluxed for 10 hours, and cooled. The mixture was concentrated, and the residue was chromatographed on silica gel, with toluene-EtOAc (1:2), to give allyl 2-acetamido-3,4-di-O-acetyl-2,6-dideoxy-6-iodo-α-D-mannopyranoside (2.96 g, 88 percent);

WORKUP

后处理

  1. temperaturecooled
  2. concentrationThe mixture was concentrated
  3. customthe residue was chromatographed on silica gel, with toluene-EtOAc (1:2)